Colleen Williams, an NBC4 Los Angeles anchor, confirmed during live broadcasts that the station's chopper went down on Tuesday night and two people on the helicopter were killed.
"We are going to take a couple of minutes to think about that, process it," she said, her voice shaking with emotion.
Moments later their coverage abruptly cut off.
Fire officials, Los Angeles mayor Karen Bass and other politicians spoke during a news conference but gave no details on who perished in the crash.
After the news conference, the mayor and other officials embraced a crying NBC reporter who also was hugged by fellow journalists.
"Losing five Angelenos is very painful," Bass said.
"And I know this community of Chatsworth hit hard, will be grieving for some time."
The helicopter crashed near a large storage facility in the neighbourhood of Chatsworth in the San Fernando Valley, while news crews were covering the bus crash that left at least two people dead and six others injured, according the Los Angeles Fire Department.
At least one person killed in the helicopter crash was outside in the car park next to the commercial building, said Captain Branden Silverman, a spokesperson for the Los Angeles Fire Department.
Two people were transported to a hospital, said Rico A Gross, a fire department battalion chief.
"From the helicopter itself, it's pretty well destroyed," Silverman said.
"So we are going to have to go through the rubble and see how many victims there were on board, as well as identify the helicopter; we couldn't even see a tail."
At least four cars and two storage containers on the ground burned after the helicopter caught fire, which was quickly put out, according to officials.
More than 70 firefighters responded to the helicopter crash, according to the fire department.
About two hours before the crash, an SUV slammed into the middle of a city bus, killing at least two people and injuring six others.
NBC has confirmed the helicopter was NewsChopper4, which is operated by Angel City Air, and was used by NBCLA and Telemundo 52.
The outlet said several TV news helicopters were reporting on the bus crash before the news helicopter went down about 2km from the collision.
NBC4 and Telemundo 52 Los Angeles said they were "deeply saddened" to learn of the helicopter crash and extended "heartfelt condolences to the families, friends and colleagues of those who lost their lives".
The National Transportation Safety Board and the Federal Aviation Administration said it would be investigating the cause of the helicopter crash and would be sending one of its investigators on Wednesday.
There have been at least eight fatal crashes involving news helicopters in the US since 2000, killing 16 people, according to a review of federal accident records and news accounts.
with Reuters