More than two tonnes of tobacco has been seized in the states south.
Police received information that a large illegal tobacco crop was being grown on a property in Berrigan earlier this week.
Investigators from the Murray River Police District went to the property about 3.45pm on Monday, April 13 and discovered about three tonnes of tobacco leaf drying.
The property was established as a crime scene and held overnight by police.
Just after 10am on Tuesday, April 14, police seized three motor vehicles, electronic devices and documentation from the property after securing a crime scene warrant.
Police reported the crop will be destroyed.
Murray River Police District Commander Superintendent Paul Smith thanked the community for continuing to provide valuable information.
"We rely on members of our community to be our eyes and ears, particularly in rural areas," Superintendent Smith said.
"As this investigation continues, we are appealing for anyone else in the community with information to come forward."
Police are working alongside investigators from the Australian Taxation Office and the Australian Border Force-led Illicit Tobacco Taskforce.
As inquiries continue, anyone with information is urged to contact Murray River Police or Crime Stoppers on 1800 333 000.