The three-week-old boy died in Queensland Children's Hospital on July 22, 2024, from internal injuries, police said.
Family members admitted him on July 18, 2024, in a serious condition, but with no obvious injuries.
"Sadly and unfortunately, that three-week-old child passed away four days later," Detective Acting Inspector Glen Antonie told reporters on Monday.
The boy's death triggered a lengthy police investigation.
Hank Shannon Sherriff, 25, was charged on Monday with the child's murder.
Investigators allege the baby was injured at a home in Greenbank in Logan, south of Brisbane, before relatives took him to hospital.
Detective Acting Inspector Glen Antonie said police were satisfied Sherriff's alleged offending met the threshold for a murder charge.
Sherriff's case was briefly mentioned in the Brisbane Magistrates Court on Monday.
He was remanded in custody to appear in Beenleigh Magistrates Court on February 25.